But how does exercise help?
But Friedenreich wanted to specifically tease apart what physiologic effects exercise has on the body, specifically on fat, since fat levels have been linked to a higher risk of a number of cancers, including breast cancer.
Importantly, the researchers requested the women, who ranged in age from 50 to 74, not change their usual diets.
Though it was known earlier that defects in protein cousins of RAD51 also had an important role to play in enhancing cancer risk in women, the researchers were not sure of the mechanism involved.
Guidelines recommend activity at least 150 minutes a week to prevent diseases.
For those who stuck with it, the average time spent working out fell just shy of the prescription with 137 of the 150 minutes, or 91%, and 254 of the 300 minutes, or 85%.
Christine M. Friedenreich, Ph.D., of Alberta Health Services, Canada, and colleagues compared 300 minutes of exercise per week with 150 minutes per week of moderate to vigorous aerobic exercise for its effect on body fat in 400 inactive postmenopausal women who were evenly split into the two exercise groups. Subcutaneous abdominal fat, as well as total abdominal fat, BMI, waist circumference, and waist-to-hip ratio also decreased more in the 300-minute group.
Be aware that the reduction in weight was not significantly different between groups, calling into question the BMI findings (unless height changed deferentially during the course of the study).
The more exercise, the better: That’s the message a group of researchers is delivering to postmenopausal women. They all had a body mass index (BMI) that fell in the range of 22 to 40, had not used exogenous hormones, were not smokers, and had never had a cancer diagnosis or any other major comorbid conditions. The main outcomes that we will assess in this trial will include accuracy of breast cancer risk perceptions, appropriate referrals to the high-risk breast clinic, and actual chemoprevention uptake.
Dr. Visvanathan said in an explanation that the increase in weight could predict whether or not an individual is at risk to other chronic illnesses, like heart disease, diabetes and high blood pressure.
On the basis of information about the patient, the original tumour and the treatment used, they can accurately predict the odds of recurrence of breast cancer per year.
“Understanding the nuts and bolts of cancer is vital if we are to beat this disease”.