Also on Monday, the 21st-seeded Madison Keys came back from a set down to upend Olga Govortsova 3-6, 6-4, 6-1.

For America’s women tennis pros, this impressive Wimbledon is merely the latest achievement in a fine year.

With Madison Keys and CoCo Vandeweghe also winning Monday, it’s the first time three American women have reached the Wimbledon quarterfinals since Serena, Lindsay Davenport and Jennifer Capriati did it in 2004.

Sharapova was well below her best on Centre Court, making 23 unforced errors, serving 10 double faults and hitting only 19 winners.

As for the match, “it was really good for me to get it done in straight sets and just put this behind me and move forward”, she said.

“I went into the match very focused and prepared because I knew that she was going to try to make it a long and physical match against me”, said Muguruza.

Prior to this year’s tournament at SW19, Vandeweghe had not been past the third round of any Grand Slam. “I need to go out there and prove myself, and that’s it. To talk about it is pointless for me”.

Sharapova endured her toughest test so far but still made it through to the quarter-finals with a 6-4, 6-4 win over Kazakhstan’s unseeded Zarina Diyas. She would hold all four major titles if she wins Wimbledon. Azarenka held three match points over Williams in Madrid, but betrayed her cause with double faults.

“I definitely am the type of person that likes to have a laugh at themselves, especially when it looks like I have done something stupidly ridiculous”, she said. “I think that relaxes me instead of keeping it pent up and at a shorter fuse”. “It’s been a while since there have been that many Americans in the second week and it’s just really exciting”, Keys said. Keys needed three sets to win in the first round and three on Monday in the fourth round.

Although Govortsova has been playing some of the best tennis she can in the lead up to this match, it’ll be hard for her to combat Keys’ aggressive style of play and pure power. “That’s a different pressure than I’m putting on myself”.

Wozniacki, who has been the world number one despite never having won a Grand Slam, was the only top 12 player left in the bottom half of the draw.

Keys has a tough task in the quarterfinals when she takes on 13th-seeded Agnieszka Radwanska of Poland.

Timea Bacsinszky vs Garbine Muguruza is the two first-time Wimbledon quarter-finalists who will face off on Tuesday. Muguruza upset fifth-seeded Dane Caroline Wozniacki 6-4, 6-4 on Monday.

Madison Keys of the U.S. is through to the women’s quarter-finals at Wimbledon.

The Russian fourth seed won Wimbledon 11 years ago but has only made it past the fourth round once since 2006. It has included a semifinal showing at the Australian Open in which she defeated Petra Kvitova and Venus Williams, and a final showing in Charleston. Denis Kudla, the last red-white-and-blue blooded American male at Wimbledon, exited in four sets to Marin Cilic.